Serious systemic infections with these organisms are unusual, but they may occur in individuals with predisposing underlying illnesses. Communityacquired pneumonia due to pasteurella multocida. The bacterium has morphological similarities with other causative organisms, particularly haemophilus influenzae, and its. In 1878, pasteurella multocida was discovered in birds infected with cholera. They cannot cause pneumonia on their own, but are usually opportunistic infections, associated with enzootic pneumonia infections, prrs, or influenza. I report the case of an elderly man who owned 16 cats and developed bacteremic pneumonia with p. Pigs suffering from an infection with toxigenic pasteurella multocida strains develop atrophic rhinitis characterised by a loss of turbinate bones and conchae. A 65yearold man was seen with an asymptomatic solitary pulmonary nodule of at least five months duration. It is caused by infection with bacteria of the pasteurella genus. Pasteurella multocida is a rarely described opportunistic pathogen of squirrel and owl monkeys affecting recently shipped animals and animals in poor condition greenstein et al. Pasteurella multocida is a leading cause of respiratory diseases in many host species.
It can also cause a zoonotic infection in humans, which typically is a result of bites or scratches from. Pasteurella multocida definition of pasteurella multocida. Recently it was found that pmt activates the serinethreonine. In humans, pasteurella multocida infections are usually limited to the soft tissues surrounding a lesion. However, the virulence properties of the different subspecies for various hosts have not been elucidated. Sep 14, 2015 pasteurella multocida toxin pmt is a potent inducer of osteoclast formation. For patients with penicillin allergies, secondline agents include. Nevertheless, prosthetic joint infection caused by p.
Pasteurella multocida is known to form part of the normal flora in the nasopharynx or gastrointestinal tract in many domestic and wild animals. However, there has been no report of this organism presenting as a flexor tenosynovitis. Pasteurella sp are a genus of zoonotic bacteria meaning they can be passed between animals and people. Microbiology legend cycle 40 organism 3 pasteurella.
File name files of type experiment file as template international units no international units pasteurella multocida 8 genesig easy kit handbook hb10. Pasteurella multocida often exists as a commensal in the upper respiratory tracts of many livestock, poultry, and domestic pet species, especially cats and dogs. In this study we investigated the antimicrobial susceptibility to 18 antimicrobial agents of 156 clinical isolates of p. Pasteurella multocida strains of the species are currently classified into five serogroups a, b, d, e, f based on capsular composition and 16 somatic serovars 116. Pasteurella multocida simple english wikipedia, the free. Pasteurella species may cause zoonotic infections of humans. Detection of bovine respiratory syncytial virus, pasteurella. The aim of this study was to determine the predisposing effect of bovine respiratory syncytial virus brsv on pasteurella spp. Painful local inflammation after animal bites in humans deserves a search for pasteurella multocida, which shows a sensitivity to penicillin unusual in a gram negative bacterium. Common symptoms of pasteurellosis in humans include swelling, cellulitis, and bloody drainage at the site of the wound. Squirrel monkeys presented with unsteady gait, nystagmus, head tilt, and circling. Antimicrobial susceptibility studies are essential for initiating rational and effective empirical therapy of p.
This volume brings together contributions from experts in the field of pasteurella research. Pasteurella multocida type a as the primary agent of. Pasteurella multocida as well as bordetella bronchiseptica is a normal inhabitant of the upper. Aureomycin and terramycin treatment of pasteurella multocida infection and neomycins in vitro effects on p. We describe a patient with a urinary tract infection uti caused by pasteurella multocida. The species pasteurella multocida includes a heterogeneous group of gramnegative bacteria that are inhabitants of the upper respiratory tract of many vertebrate hosts, including birds, cattle, swine, cats, dogs and rodents. This is a pdf file of an article that has undergone enhancements after acceptance, such as the addition. Pasteurella multocida had 5 antigenic groups ae types.
Pneumonic pasteurellosis is an economically significant infectious disease of ruminants, and the main etiological agent is pasteurella multocida, a nonhemolytic, gramnegative. Pasteurella multocida urinary tract infection with molecular. Isolation, identification, characterization and antibiogram of. Pasteurella multocida is primarily a veterinary pathogen that produces septicemic or respiratory diseases in both domesticated and wild mammals and birds. Pulsedfield gel electrophoresis revealed that the clinical isolate recovered from the patient was identical 100% band match to p. Pasteurella multocida infections after domestic animal bites and scratches donald p. Pdf pasteurella multocida mastitis in cow case report. Infection with pasteurella multocida following cat bite. Links to pubmed are also available for selected references. Pasteurellosis is an infection with a species of the bacterial genus pasteurella, which is found in humans and other animals pasteurella multocida subspecies p. Pasteurella multocida subspecies multocida is the most common cause of fowl cholera, although p. Haemorrhagic septicaemia or pasteurellosis is a peracute to acute, highly fatal bacterial disease, principally of cattle and water buffaloes bubalus bubalis, in which the gramnegative pasteurella multocida. Multidrug resistant pasteurella multocida strains isolated. Primerdesign ltd tm pasteurella multocida genesig easy kit.
Pasteurella multocida is a gramnegative, nonmotile, penicillinsensitive coccobacillus of the family pasteurellaceae. Get a printable copy pdf file of the complete article 1. Pasteurella multocida bacteremia in an immunocompromised patient. Pasteurella multocida type b african wildlife diseases.
More detailed information about the symptoms, causes, and treatments of pasteurella multocida is available below. Pdf antimicrobial resistance of pasteurella multocida isolates. Genetic and phylogenetic characteristics of pasteurella. Based on the conventional serotyping method, the 114 strains of p. We report here a series of six cases of prosthetic joint infection caused by p. Pasteurella multocida peritonitis another risk of animal assisted therapy volume 25 issue 1 john sillery, james hargreaves, philip marin, edgar lerma, cathy kuznia, claudette abbe. Pasteurella multocida an overview sciencedirect topics. Infections are usually transmitted to humans as a result of cat scratches and cat or dog bites but can also rarely be seen following licks from these animals 2. Pasteurella multocida infections do cause significant lung damage in coinfections making it a. Pasteurella multocida involved in respiratory disease of. A case of unexpected pasteurella multocida bacteremia. In order to understand better the pathological aspects and spread of pasteurella multocida type a as the primary cause of pneumonia in pigs, was made an experiment with intranasal inoculation of different concentrations of inocula group g1.
Pasteurella multocida is a gramnegative nonmotile coccobacillus that causes pasteurellosis, also known as snuffles, the primary respiratory disease affecting domestic rabbits deeb and digiacomo, 2000. Characteristics of pasteurella multocida of human origin. Pasteurella multocida is a gramnegative, coccobacillus belonging to the pasteurellaceae family. Pasteurella multocida is responsible for economically important diseases in sheep and pigs. Gatf is the galactosyltransferase which adds gal i to the 4th position of the glc iv 38. In addition, sera from 40 sheep were aseptically collected and examined to evaluate level of protective antibody titer before and after p. It is often transmitted through bites and scratches from pets and it can be found in mammals and fowl. Pasteurella multocida charles river research animal. Pasteurella multocida lehmann and neumann 1899 rosenbusch and merchant. However, on the molecular level the process of bone loss remains largely uncharacterised. Pasteurella multocida type a strains are usually involved in respiratory diseases in swine. Jun 26, 2018 pasteurella multocida is a leading cause of respiratory diseases in many host species. Pasteurella multocida, multidrug, resistance, chickens, jos introduction fowl cholera is a contagious bacterial disease that affects both domestic and wild. The aim of this study was to characterise and compare pasteurella multocida isolates originating from pigs n 43, calves n 31, rabbits n 27.
Capsular serotyping of pasteurella multocida from various. Clinical features and outcomes of pasteurella multocida. Its covers areas such as comparative genomics, pathogenic mechanisms, bacterial proteomics, as well as a. Pasteurellosis is most commonly seen in pigs as a complication of mycoplasmal pneumonia see mycoplasmal pneumonia, although swine influenza, aujeszky disease, bordetella bronchiseptica, or haemophilus parahaemolyticus may also cause changes in the lungs that lead to disease caused by pasteurella spp. Pdf pasteurella multocidainduced endophthalmitis after. The bacterium has morphological similarities with other causative organisms, particularly haemophilus influenzae, and its apparent rarity may be due partly to misidentification. Pasteurella multocida involved in respiratory disease of wild. There are a number of species and sub species, but all are quite similar 2. Pasteurella multocida peritonitis another risk of animal. Bacterium mutocidum lehmann and neumann, 1899, micrococcus gallicidus burrill, 1883 common names.
Pasteurella multocida appears to be a very rare cause of meningitis. Full text get a printable copy pdf file of the complete article 4k, or click on a page image below to browse page by page. Pubmed is a searchable database of medical literature and lists journal articles that discuss pasteurella multocida infection. Haemorrhagic septicaemia or pasteurellosis is a peracute to acute, highly fatal bacterial disease, principally of cattle and water buffaloes bubalus bubalis, in which the gramnegative pasteurella multocida serotypes b.
Pasteurella multocida grown under ironlimited conditions also induces a stronger protective response in mice compared with the same strain grown under ironreplete conditions kennett et al. Pasteurella questions and study guide quizlet flashcards by. Pasteurella multocida is a facultative anaerobic, fermentative gramnegative coccobacillus found in the oropharynx of healthy animals, particularly cats, dogs, and pigs, as well as various wild animals. Characterisation and comparison of pasteurella multocida. Surgical resection of the lesion showed an acute and chronic lung abscess histologically, and culture again yielded p multocida.
Pasteurella multocida article about pasteurella multocida. During october 2014, the minnesota department of health was notified of five hospital a patients with pasteurella multocida. They are a natural inhabitant of the skin, digestive tract and oral cavity of cats, but can cause disease under the right conditions. A pasteurella multocida gatf mutant al2116 was also used that was unable to assemble the external core of lps beyond glc iv.
Get a printable copy pdf file of the complete article 857k, or click on a page image below to browse page by page. Strains of the species are currently classified into five serogroups a, b, d, e, f based on capsular composition and 16 somatic serovars 116. Pasteurella multocida, a gramnegative, facultative anaerobic, nonsporeforming pleomorphic coccobacillus, is a commensal bacterium and part of the natural flora in the nasopharynx and upper respiratory tract of the cat freshwater, 2008. Pasteurella multocida involved in respiratory disease of wild chimpanzees plos one, sep 2011 sophie kondgen, michaela leider, felix lankester, astrid bethe, antina lubkebecker, fabian h. Pasteurellosis swine diseases manual pig333, pig to pork. Recovery and identification of pasteurella multocida from mammals and fleas collected during plague investigations. Pasteurella haemolytica is a species that infects mainly cattle and horses. Pdf pasteurella multocida and bovine respiratory disease. During october 2014, the minnesota department of health was notified of five hospital a patients with pasteurella multocida bacteraemia. Pasteurella multocida toxin induced osteoclastogenesis. Gatlin brandon, ms, mph pasteurella multocida is a common cause of. Insights into the genome sequence of ovine pasteurella. An infectious disease caused by a bacterium called pasteurella multocida. Pasteurella multocida is a pathogenic gramnegative bacterium that has been classified into three subspecies, five capsular serogroups and 16 serotypes.
Pdf pasteurella multocidainduced endophthalmitis after a. Antimicrobial susceptibility of pasteurella multocida. Pasteurella multocida, a gramnegative oral commensal of most dogs and cats. Isolation, identification, characterization and antibiogram of pasteurella multocida.
Pasteurella multocida is the most commonly reported organism in this group, and is well known. The organism can occur as a commensal in the nasopharyngeal region of apparently healthy animals. Full text is available as a scanned copy of the original print version. Prosthetic joint infection caused by pasteurella multocida. Berberine, pasteurella multocida, antibacterial activity, mechanism introduction p.
Pasteurella multocida is a wellrecognized zoonotic agent following dog or cat bites or scratches. The bacteria typically appear as single bacilli on gram stain. Click on the link to view a sample search on this topic. Pasteurella multocida is a gramnegative, nonmotile coccobacillus that is penicillinsensitive. Pasteurellosis in pigs respiratory system veterinary manual.
Pasteurella multocida septicemia and subsequent pasteurella. Pdf a total of 32 pasteurella multocida isolates were obtained from 60 cases of swine pneumonic lungs collected in castilla y leon northwestern. Rimler, in encyclopedia of immunology second edition, 1998. Text is available under the creative commons attributionsharealike license. Experimental pneumonia in rabbits inoculated with strains of. Original article antibacterial activity and mechanism of. This case, only the fourth reported from the united kingdom. Rhinosinusitis possibly caused by pasteurella multocida. Pasteurella multocida type a as the primary agent of pneumonia and septicaemia in pigs. Pasteurella multocida are small gramnegative coccobacilli, commonly found in oral microbiota of 60% of dogs and 7090% of cats. Pasteurella multocida, a small, gramnegative coccobacillus, is part of the normal. Culture of a percutaneous needle aspirate yielded pasteurella multocida. Nov 07, 2019 pasteurella multocida is a small, gramnegative, nonmotile, nonsporeforming coccobacillus with bipolar staining features. Pasteurella multocida has been described as a pathogen in hand infections following animal bites.1045 993 63 868 1306 1354 1410 1553 1637 753 1058 1475 840 1181 213 672 753 1409 1613 1016 1637 462 1000 1366 360 708 695 709 422 1635 572 1536 726 1259 75 640 446 557 644 297 781 785 261 327